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含基酸基结合微孔聚合物,用于环境和食品样本中诺基诺抗生素的固相提取

Lu-Shu Meng¹, Xiao-Li Wang¹, Xia Wang¹

¹Qilu University of Technology (Shandong Academy of Sciences), Shandong Analysis and Test Center, Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province, Jinan 250014, China.

|March 6, 2024

概括

研究人员开发了一种新方法,使用含基酸基结合微孔聚合物 (CMPs-OH) 来检测环境和食品样本中的微量诺 (FQs). 这种方法为抗生素残留分析提供了灵敏而高效的丰富剂.

科学领域:

分析化学分析化学
环境科学环境科学
食品安全食品安全

背景情况:

诺基诺 (FQs) 是广泛使用的抗生素,在环境和食品矩阵中对敏感检测提出了挑战.
精确确定微量FQ对于环境监测和确保食品安全至关重要.
现有的方法往往缺乏足够的灵敏度和效率来进行微量级分析.

研究的目的:

开发一种有效和敏感的样本预处理方法,用于确定微量化诺 (FQs).
为了利用新的含基酸基结合微孔聚合物 (CMPs-OH) 作为固相提取 (SPE) 吸收剂.
在复杂的环境和食品样本中建立可靠的分析方法来监测FQ.

主要方法:

构建含基化基结合微孔聚合物 (CMPs-OH) 的构造.
应用CMPs-OH作为固相提取 (SPE) 吸收剂用于FQ丰富.
使用高性能液体染色学-并联质谱法 (HPLC-MS/MS) 量化FQs.

主要成果:

CMPs-OH 显示出 FQ 的优异缩能力,这归因于结和 π-π 相互作用.
开发的方法表现出广泛的线性范围 (0.2-400 ng L-1) 和低的检测极限 (0.05-0.15 ng L-1).
在对14个现实环境和食品样本的分析中,获得了很高的恢复率 (82.6%109.2%).

结论:

开发的基于CMPs-OH的SPE方法为微量FQ确定提供了可行和高效的方法.
这种方法显著提高了环境和食品矩阵中化诺残留物监测的灵敏度和准确性.
这项研究为监管机构和专注于抗生素污染的研究人员提供了宝贵的工具.

关键词:

结合的微孔聚合物.诺基诺抗生素是一种抗生素.在HPLC-MS/MS中使用.固体相提取的固体相提取方法

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