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Updated: Jul 1, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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用Ligand Designer来定制烯--COX抑制剂的精确切割

Huy Hoang Nguyen Vo1, Thu Huong Thi Phung2, Khanh Linh Chung1

  • 1Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City, Viet Nam.

Journal of molecular graphics & modelling
|March 6, 2024
PubMed
概括

研究人员设计了新型化合物来抑制循环氧化酶1和2 (COX-1/2) 酶,这是炎症的关键参与者. 化合物9和10表现出优越的结合亲和力,显示出作为新的抗炎药物候选者的希望.

关键词:
抗炎药物是一种抗炎药物.这是一种COX抑制剂.连接体设计师是什么意思量身定制的化学虚拟选是一个虚拟的选.

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