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酸缓冲剂改善了pazopanib在胃酸抑制的老鼠模型中的溶解性和吸收性

Huda Jassim Muhammad1, Tsutomu Shimada2, Arimi Fujita2

  • 1Department of Clinical Pharmacokinetics, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8641, Japan; Department of Clinical Pharmacy, College of Pharmacy, Karbala University, Karbala, 56001, Iraq.

Drug metabolism and pharmacokinetics
|March 6, 2024
PubMed
概括

帕佐帕尼布的吸收被质子抑制剂减少. 在服用这些药物的患者中,将帕佐帕尼布与酸缓冲剂一起使用可以显著改善其吸收.

关键词:
吸收方式 吸收方式酸性饮料是一种酸性饮料.酸的使用方法这就是Pazopanib.药理动力学 药理动力学可溶性 可溶性 溶性

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