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患有牙损伤的青少年的口腔微生物群:系统性审查

Francien Veenman¹, Anne van Dijk², Alexandre Arredondo³

¹Department of Oral and Maxillofacial Surgery, Special Dental Care and Orthodontics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.

Archives of oral biology

|March 6, 2024

概括

口腔微生物群的组成在有牙和没有牙的青少年之间有所不同. 某些细菌物种,如Streptococcus mutans可能会增加脏病的风险,需要进一步的纵向研究.

科学领域:

口腔微生物学口腔微生物学
牙科公共卫生牙科公共卫生
青少年健康青少年健康

背景情况:

牙损仍然是一个重要的全球健康问题,特别是在青少年中.
了解口腔微生物群在病发展中的作用,对于有效的预防策略至关重要.

研究的目的:

系统地审查和综合有关口腔微生物群组成和青少年牙之间的关联的当前知识.
鉴定特定的细菌种群,可能与这个年龄组的脏病风险增加有关.

主要方法:

对五个数据库进行了全面的电子搜索.
包括的研究使用了对一般健康青少年的基于分子的微生物学分析,并评估了病状况.
数据提取和质量评估由两名独立审查员使用纽卡斯尔-太华尺度进行.

主要成果:

分析了20项横截面研究 (2005-2022年) 涉及3935名参与者 (年龄11-19岁).
像 (q) PCR 和下一代测序等分子方法用于唾液,牙生物膜或舌头拭子.
在患有空的青少年中,经常发现Prevotella denticola,Scardoviae Wiggsiae,Streptococcus sobrinus和Streptococcus mutans的数量较高.

结论:

口腔微生物群的组成似乎在有牙和没有牙的青少年之间有所不同.
特定的细菌种类可能与患牙的风险增加有关.
需要进行更大规模的纵向研究来证实这些发现,考虑到的严重程度和青少年特定因素.

关键词:

细菌细菌是一种细菌.增长/发展增长/发展微生物组是一个微生物组.风险因素 (风险因素)突变型链球菌 (Streptococcus mutans) 是一种流感菌.

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