STING-IRF3,BRD4LPS

Ruigong Zhu1, Lei Zhang2, Hao Zhang3

  • 1School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing City 210023, China; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang City 550014, China.

Cellular signalling
|March 6, 2024
PubMed
概括

odomain 4 (BRD4) 通过激活STING通路来加速内皮细胞衰老. BRD4 抑制STING降解并促进炎症反应,为心血管疾病提供新的治疗点.

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