[唾液腺瘤:2022年世界卫生组织蓝皮书及以后]
1Service d'anatomie et cytologie pathologiques, University Hospital Centre Nantes, Nantes université, CHU de Nantes, 44000 Nantes, France; Inserm, INCIT, UMR 1302/EMR6001, CNRS, Immunology and New Concepts in ImmunoTherapy, Nantes, France.
Annales de pathologie
|March 6, 2024
概括
2022年世界卫生组织分类更新了唾液腺瘤,引入了新的良性实体,如角囊瘤,并修订了其他实体. 恶性瘤分类也发生了变化,发现了新的腺癌,并重新评估了细胞癌.
科学领域:
- 头和部病理学 头部和部病理学
- 瘤的分类 瘤的分类
- 唾液腺新生体 新生体
背景情况:
- 世界卫生组织 (WHO) 的分类系统对于标准化瘤诊断至关重要.
- 以前的唾液腺瘤分类已经根据不断发展的研究进行了修订.
- 准确的分类会影响患者的管理和治疗策略.
研究的目的:
- 总结2022年世界卫生组织第五版头瘤分类中的关键变化,特别关注唾液腺瘤.
- 要突出新引入和重新分类的良性和恶性唾液腺实体.
- 提供影响唾液腺瘤诊断的重大更新的概述.
主要方法:
- 审查2022年第五版世卫组织头部和部瘤分类.
- 唾液腺瘤章节内的变化的分析.
- 新描述和修订的瘤实体的识别和分类.
主要成果:
- 介绍囊瘤作为一个新的良性实体.
- 变质性多囊性腺瘤重新归类为变质性多囊性腺瘤.
- 线状管腺瘤现在有一个专门的章节.
- 包括一种新的多形腺瘤变体",状腺瘤样",包括在内.
- 瘤细胞癌因诊断不确定性而被重新归类为新兴实体.
- 两个新的恶性实体的出现:微分泌腺癌和微囊性硬化腺癌.
- 唾液腺的初级粘膜腺癌被认为是一个独特的实体.
结论:
- 世卫组织2022年分类显著更新了唾液腺瘤的景观.
- 这些修订反映了理解瘤生物学和形态学的进步.
- 更新的分类为诊断和管理唾液腺瘤提供了一个精细的框架.
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