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Updated: Jul 1, 2025

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage
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Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage

Published on: August 21, 2021

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通过KTN1介导的未折叠蛋白质反应保护质细胞免受电离辐射诱导的DNA损伤

Xinli Niu1, Yi Shen1, Yunhan Wen1

  • 1Department of Radiation Medicine, Guangdong Provincial Key Laboratory of Tropical Disease Research, NMPA Key Laboratory for Safety Evaluation of Cosmetics, School of Public Health, Southern Medical University, Guangzhou, China.

Journal of dermatological science
|March 6, 2024
PubMed
概括

电离辐射 (IR) 激活了皮肤细胞中的未折叠蛋白质反应 (UPR). UPR可以防止IR诱导的DNA损伤,KTN1蛋白在这种保护机制中发挥着关键作用.

关键词:
造成的DNA损伤是DNA损伤.电离辐射辐射的电离辐射.在KTN1中,KTN1是KTN1.氨酸细胞 (keratinocyte) 是一种细胞.不折叠的蛋白质反应反应

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