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Labeling DNA Probes03:31

Labeling DNA Probes

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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相关实验视频

Updated: Jul 1, 2025

Visualizing Lignification Dynamics in Plants with Click Chemistry: Dual Labeling is BLISS!
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粘性多色机色标签 粘性多色机色标签

Lucas D C de Castro1,2, Tom A P Engels3, Osvaldo N Oliveira1

  • 1São Carlos Institute of Physics, University of São Paulo, São Carlos 13566-590, SP, Brazil.

ACS applied materials & interfaces
|March 6, 2024
PubMed
概括
此摘要是机器生成的。

研究人员开发了动态粘贴标签,在拉伸时会改变颜色. 这些可适应的机色标签为智能材料和需要在变形时视觉反的应用提供了新的可能性.

关键词:
胆固醇的液晶弹性体是一种液晶弹性体.标签是标签上的标签.机色设备是机色的设备.贴纸 贴纸 贴纸 贴纸可穿戴设备可穿戴设备.

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科学领域:

  • 材料科学 材料科学 材料科学
  • 聚合物化学 聚合物化学
  • 光学是什么?光学是什么?光学是什么?

背景情况:

  • 传统的粘贴标签是静态的,缺乏动态的视觉反功能.
  • 材料的机械变形往往在视觉上没有说明.
  • 需要适应性强的材料,可以在对物理变化的反应中提供视觉线索.

研究的目的:

  • 引入一种具有机色特性的动态粘贴标签的新型类别.
  • 展示一种方法来创建响应机械刺激的有图案的结构颜色.
  • 探索这些响应式标签的潜在应用.

主要方法:

  • 基于胆固醇液晶弹性体 (CLCE) 的粘性机色标签的开发.
  • 使用紫外线 (UV) 交联与光罩来打印结构色彩图案.
  • 控制交叉连接度和体积反应,在拉伸时诱导颜色变化.

主要成果:

  • 成功创建了动态粘贴标签,在拉伸时显示结构色彩变化.
  • 展示了一种始终可见或可逆地显示/隐藏的印记模式的方法.
  • 由于Poisson比率对比,观察到潜在的色彩分离效应.

结论:

  • 开发的粘性机色标签通过结构性颜色变化为视觉通信提供了一个新的平台.
  • 这些标签适用于各种表面,包括柔性和脆性材料.
  • 潜在的应用包括压力-应变传感,智能服装,安全功能和装饰元素.