3Mixtatin与MTA在初级牙的纸治疗中:当前随机对照试验的系统审查和元分析
Mobina Sadat Zarabadi1, Parsa Firoozi2, Samira Basir Shabestari3
1Department of Pediatric Dentistry, School of Dentistry, Zanjan University of Medical Sciences, Zanjan, Iran.
Evidence-based dentistry
|March 6, 2024
概括
3Mixtatin在初级牙肉质治疗中表现出与矿物三氧化物聚合物 (MTA) 相比的临床和放射性成功. 这种新的生物材料显示出作为目前内牙科黄金标准的替代品的希望.
科学领域:
- 儿科牙科 儿科牙科
- 牙周内科医院 牙周内科医院 牙周内科医院
- 生物材料科学 生物材料科学
背景情况:
- 矿物三氧化物聚合物 (MTA) 是主要牙中纤维治疗的黄金标准.
- 3Mixtatin是一种新型生物材料,结合了美特罗尼达,米诺环素,西普罗夫洛克萨和他类药物,为纸治疗提供了一个新的选择.
研究的目的:
- 为了比较3Mixtatin与MTA在一次性牙脉治疗中的临床和放射性成功率.
主要方法:
- 一个系统的审查和随机对照试验 (RCTs) 的元分析发表到2023年2月.
- 搜索了包括MEDLINE (PubMed),CENTRAL,科学网,Scopus,ProQuest和谷歌学者在内的数据库.
- 使用柯克兰偏差风险 (RoB-2) 工具评估偏差风险,并使用风险比率 (RRs) 评估效应大小.
主要成果:
- 四个RCT符合纳入标准,所有RCT都显示偏差风险较低.
- 在12个月后,3Mixtatin的临床 (RR=1.087) 和放射性 (RR=2.132) 成功率与初级牙肉治疗中的MTA相似.
结论:
- 有限的证据表明,3Mixtatin是一种临床和放射性有效的替代MTA用于母牙肉治疗.
- 需要进一步严格研究更大的样本大小来证实这些发现.
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