先天性毒素菌和长期的结果
Ozlem Ozgur Gundeslioglu1, Zeliha Haytoglu2, Ebru Esen3
1Cukurova University Faculty of Medicine, Department of Pediatric Infectious Diseases, Adana, Türkiye.
Turkiye parazitolojii dergisi
|March 7, 2024
概括
先天性毒素菌 (CT) 可以导致严重的视力,听力和神经发育问题. 婴儿CT的早期诊断和治疗对于预防长期并发症至关重要.
科学领域:
- 医学研究 医学研究
- 传染性疾病 传染性疾病
- 儿科 儿科 儿科
背景情况:
- 遗传性毒素瘤 (CT) 对儿童造成严重的早期和晚期并发症的风险很大.
- 了解CT的人口,临床和治疗特征对于有效管理至关重要.
研究的目的:
- 评估被诊断患有先天性毒素菌症的患者的人口,临床和治疗特征.
- 为了突出与先天性毒素菌相关的长期并发症.
主要方法:
- 在2010年至2022年间,对CT患者进行了回顾性分析.
- 诊断包括Toxoplasma IgM,IgG,IgG热度和PCR测试,以及临床评估.
- 收集了母亲和婴儿数据,包括治疗和结果.
主要成果:
- 研究了18名CT儿童;眼部卷入 (55.5%) 是最常见的,其次是水头和内结 (27.7%).
- 长期的后果包括神经发育迟缓 (38.8%),听力损失 (11.1%),发作 (16.6%) 和小头症 (11.1%).
- 孕妇在怀孕期间接受螺旋素治疗显示出一些保护作用,尽管在一个案例中发生了微症.
结论:
- 先天性毒素菌导致严重的后果影响视力,听力和神经发育.
- 怀孕期间早期检测Toxoplasma感染,及时治疗婴儿对于预防严重后果至关重要.
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