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对3个肝脏磁共振弹性成像系统的比较研究

Runke Wang^1,2,3,4, Yikun Wang^1,5, Suhao Qiu^1,2,3,4

¹Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Journal of magnetic resonance imaging : JMRI

|March 7, 2024

概括

不同的MR弹性图 (MRE) 系统显示出对肝硬度测量的良好可重现性,尽管绝对值的变化. 这种一致性支持使用MRE技术的多中心研究.

科学领域:

医疗成像医学成像
生物物理学的生物物理.
放射学放射学是指放射学

背景情况:

磁共振弹性图 (MRE) 系统可以产生不同的刚度测量.
这种变化在多中心研究中给直接比较带来了挑战.

研究的目的:

为了评估肝硬度测量的可重复性和可重复性,在三个不同的MRE系统中进行测量.
评估MRE肝硬度量化中的观察者间,扫描间和系统间的变异性.

主要方法:

一项前性研究,涉及30名健康志愿者和5名凝幽灵.
使用了三个MRE系统:3.0T UIH,1.5T西门子和3.0T GE,采用基于Echo Planar成像的MRE序列.
统计分析包括类内相关系数 (ICC),变化系数 (CV),布兰德-阿尔特曼分析,配对t测试和弗里德曼测试.

主要成果:

观察到高的观察者间可重复性 (ICC > 0.92,CV < 4.32%) 和优异的间扫描可重复性 (ICC > 0.96,CV < 3.86%).
肝脏评估的系统间可重复性显示出良好的结果 (ICCs 0.70-0.87,CVs 6.46%-10.99%),系统间绝对刚度值有显著差异.
幻影研究证实了这些发现,表明不同MRE平台的性能一致.

结论:

肝硬度测量在不同的MRE系统之间有所不同.
尽管存在定量差异,但MRE系统表现出良好的可重复性,支持其在多中心调查中的使用.
标准化或校准可能有利于精确的跨系统比较.

关键词:

肝脏肝脏肝脏肝脏肝脏肝脏磁共振弹性图形学磁共振弹性图形学可以重复的可重复性.可复制性的可复制性系统比较系统比较组织硬,组织硬.

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