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基于神经网络模型的linezolid诱导的血小板缺血风险因素的预测

Xian Zhao1, Qin Peng2, Dongmei Hu1

  • 1Department of Pharmacy, First Affiliated Hospital of Air Force Medical University, Xi'an, Shaanxi, China.

Frontiers in pharmacology
|March 7, 2024
PubMed
概括

人工神经网络准确地预测了linezolid诱导的血小板缺血风险因素,优于传统模型. 这有助于预防不良药物反应,以确保更安全的临床使用.

关键词:
在ADR中,ADR是ADR.一个年龄,一个年龄.在线zolidlid是什么意思逻辑回归的逻辑回归方法风险因素的风险因素是什么血小板细胞减少症 (Thrombocytopenia) 是一种

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Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...