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与COVID-19相关的高甘油三血和治疗的影响
Rasha Kaddoura1, Mohamed Izham Mohamed Ibrahim2, Maha Al-Amri1
1Pharmacy Department, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.
Frontiers in medicine
|March 7, 2024
概括
与COVID-19相关的高甘油三血症延长了康复和住院时间,但没有增加死亡率. 在这些患者中治疗高甘油三水平并没有改善临床结果.
科学领域:
- 密集护理医学 密集护理医学
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
背景情况:
- COVID-19 (冠状病毒疾病2019) 与ICU患者的高甘油三血症有关.
- 这种情况会影响临床结果和治疗策略.
研究的目的:
- 在ICU患者中描述COVID-19相关的高甘油三血症.
- 评估治疗高甘油三血症对临床结果的影响.
主要方法:
- 成年ICU患者患有COVID-19肺炎的回顾性观察队列研究.
- 过高甘油三血症定义为甘油三水平≥1.7 mmol/L;严重的过高甘油三血症作为Tg≥5.6 mmol/L.
主要成果:
- 82.3%的患者患有过高甘油三血症,恢复时间和住院时间显著延长.
- 治疗高甘油三血症并没有改善死亡率或恢复.
- 老年患者不太可能患上高甘油三血症或接受治疗.
- 托西利祖马布的使用与更高的TG水平和治疗有关.
结论:
- 与COVID-19相关的高甘油三血症会延长ICU和住院时间,但不会增加死亡率.
- 在COVID-19患者中治疗高甘油三血症并没有改善临床结果.
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