在腹腔透析患者中,sarcopenic肥胖和死亡率之间的关联:一个前性队列研究
Yiwei Shen1,2, Xinyu Su1,2, Zanzhe Yu1,2
1Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Frontiers in medicine
|March 7, 2024
概括
肥胖症与腹膜透析患者的生存率较差有关. 这项研究发现,与没有肥胖症的患者相比,患有sarcopenic肥胖症的PD患者的死亡风险明显增加.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 老年学是一门学科.
- 代谢疾病 代谢疾病
背景情况:
- 麻症和肥胖症在腹腔透析 (PD) 患者中很普遍.
- 萨科佩尼性肥胖对PD患者存活率的影响的综合条件尚不清楚.
研究的目的:
- 为了研究在接受腹腔透析的患者中,sarcopenic肥胖症和整体存活率之间的关联.
主要方法:
- 对PD患者进行前性观察性研究.
- 根据亚洲麻症工作组 (AWGS) 标准 (低ASMI和HGS) 定义的麻症.
- 肥胖是由身体脂肪百分比 (PBF) 定义的. 使用Kaplan-Meier,日志等级,Cox回归和CICR分析的生存率.
主要成果:
- 纳入了223名PD患者;11.2%被诊断患有sarcopenic肥胖.
- 萨尔科佩尼肥胖症组的生存率明显较低 (逻辑等级p < 0.001).
- 多变量分析表明,sarcopenic肥胖与较高的死亡率有关 (HR: 2.190,p = 0.047).
结论:
- 在PD患者群体中,sarcopenic肥胖症是一个重要的发现.
- 标本性肥胖与PD患者死亡风险增加独立相关.
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