对COVID-19的药理学药物,免疫疗法和支持性治疗方法进行了全面的审查
Khan Sharun1, Ruchi Tiwari2, Mohd I Yatoo3
1Division of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, India.
Narra J
|March 7, 2024
概括
本综述涵盖已批准和潜在的COVID-19治疗方法,包括抗病毒药物,免疫疗法和传统中医药. 它强调了对候选药物的体内数据的需求,以及支持性疗法在管理2019年冠状病毒疾病中的作用.
科学领域:
- 病毒学 病毒学
- 药理学 药理学是指药理学的学科.
- 免疫学 免疫学 免疫学
背景情况:
- 由SARS-CoV-2引起的2019年冠状病毒病 (COVID-19) 的出现需要紧急的治疗策略.
- 目前的努力集中在重新利用小分子药物上,许多通过in silico和in vitro研究确定.
研究的目的:
- 综合审查COVID-19的已批准和潜在的治疗药物.
- 探索基于免疫细胞的疗法,免疫调节剂和COVID-19治疗的营养干预措施.
主要方法:
- 对COVID-19的已批准和潜在治疗剂的文献审查.
- 对药物有效性进行的in silico,in vitro和in vivo研究的分析.
- 包括支持性疗法,如传统中医和营养干预.
主要成果:
- 几种候选药物显示出前景,但需要体内数据才能考虑临床试验.
- 包括传统中医和免疫调节剂在内的辅助疗法在治疗COVID-19患者中发挥着重要作用.
- 一些疗法已经被纳入临床指南和标准操作程序.
结论:
- 结合直接作用抗病毒药物和支持性疗法的多方面的方法对于有效的COVID-19管理至关重要.
- 通过初步研究确定的候选药物必须进行进一步的体内验证.
- 该综述提供了针对COVID-19的当前和新兴治疗策略的全面概述.
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