美国成年人中脂肪分布和糖尿病之间的关系,按种族/民族分类
Furong Xu1, Jacob E Earp2, Deborah Riebe3
1College of Education, University of Rhode Island, Kingston, RI, United States.
Frontiers in public health
|March 7, 2024
概括
在大多数群体中,内脏脂肪组织区域 (VATA) 与糖尿病有关,独立于皮下脂肪区域 (SFA). VATA和糖尿病之间的关系因种族和性别而异,突出了健康差异.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 公共卫生 公共卫生
背景情况:
- 全球糖尿病患病率正在上升,人口群体之间存在显著差异.
- 了解身体脂肪分布在糖尿病风险中的作用对于有针对性的干预至关重要.
- 现有的研究往往忽略了与脂肪相关的糖尿病风险的性别特异性和种族/种族差异.
研究的目的:
- 调查内脏脂肪组织区域 (VATA) 和皮下脂肪区域 (SFA) 与糖尿病患病率之间的关联.
- 检查这些跨不同性别特异性种族/种族群体的关联.
- 为了确定VATA或SFA是否是糖尿病的更强的预测因素,考虑其他因素.
主要方法:
- 国家健康和营养检查调查 (2011-2018) 的二次数据分析,共有11,972名参与者.
- 利用多重后勤回归来评估VATA和SFA与糖尿病的独立和同时关联.
- 对人口统计和肌肉质量进行了调整,对多次比较进行了邦费罗尼校正.
主要成果:
- 在两种性别和几乎所有种族/族群中,VATA与糖尿病有积极的关联 (p < 0.05),除了黑人女性.
- 在考虑VATA时,SFA与糖尿病没有显著的相关性,除了白人女性 (p = 0.032).
- 与黑人女性相比,白人和西班牙裔女性的VATA-糖尿病联系更强 (p < 0.005).
结论:
- 内脏脂肪 (VATA) 是不同人群糖尿病的重要预测因素,独立于皮下脂肪 (SFA).
- 皮下脂肪 (SFA) 与糖尿病有有限的独立关联,主要在白人女性中发现.
- 这些发现强调了与性别特定的种族/种族群体之间的脂肪分布有关的糖尿病风险的健康差异显著,需要进一步调查.
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