控制前列腺癌诊断的营养状况评分的预测价值
Jiaguo Huang1, Ji Sun1, Runmiao Hua1
1Department of Urology, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.
Frontiers in oncology
|March 7, 2024
概括
控制营养状况 (CONUT) 评分显示为诊断前列腺癌 (PCa) 的辅助工具. 将CONUT与PSA,PSAD和mpMRI结合起来,可以显著提高诊断准确度.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 诊断医学 诊断医学 诊断医学
背景情况:
- 前列腺癌 (PCa) 诊断依赖于各种临床因素.
- 控制营养状况 (CONUT) 评分,衡量营养状况,尚未广泛评估其在PCa诊断中的预测价值.
研究的目的:
- 调查前列腺癌 (PCa) 诊断CONUT得分的预测价值.
- 评估CONUT得分作为辅助诊断指数的有用性.
主要方法:
- 从114名接受前列腺针活检的患者的数据进行了回顾性分析.
- 使用ROC曲线分析评估CONUT得分,临床因素和PCa诊断之间的关系.
主要成果:
- 与非PCa组相比,PCa组在年龄,PSA,PSAD,PI-RADS,CONUT得分,前列腺体积,淋巴细胞计数和总胆固醇方面表现出显著差异.
- CONUT评分显示了诊断准确度 (AUC = 0.687),当与PSA,PSAD和mpMRI (AUC = 0.881) 相结合时,诊断准确度有所改善.
- 更高的CONUT分数与更高的PCa诊断阳性率有关.
结论:
- CONUT分数作为PCa诊断的有价值的辅助指数.
- 将CONUT得分与PSA,PSAD和mpMRI等已知标记器相结合,可以提高诊断性能.
- 建议对更大的队列进行进一步的前性研究,以验证这些发现.
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