牛皮关节炎患者的骨质疏松症和骨质疏松症:一个单中心的回顾性研究
Kenji Takami1,2, Mari Higashiyama2,3, Shigeyoshi Tsuji1,2,4
1Department of Orthopaedic Surgery, Nippon Life Hospital, Osaka, Japan.
Modern rheumatology
|March 7, 2024
概括
牛皮关节炎 (PsA) 患者,特别是50岁以下的男性,面临骨质疏松症和骨折的高风险. 下肢体质量指数和椎骨分数表明,在PsA中,骨质疏松症的风险增加.
科学领域:
- 类风湿病学 类风湿病学
- 内分泌学 在内分泌学.
- 整形外科 整形外科 整形外科
背景情况:
- 在牛皮关节炎 (PsA) 患者中,骨折风险较高.
- 脊髓炎和骨质疏松症之间的关系缺乏明确的共识.
- 这项研究调查了PsA患者的骨质疏松症患病率和危险因素.
研究的目的:
- 为了确定牛皮关节炎患者骨质疏松症的发生率.
- 在这个人群中识别与骨质疏松症相关的危险因素.
- 评估牛皮关节炎患者骨质疏松症的患病率.
主要方法:
- 从163名牛皮关节炎患者收集了数据.
- 骨质疏松症和骨质疏松症是使用世卫组织标准来诊断的.
- 脆弱性脊椎压缩骨折也表明骨质疏松症.
主要成果:
- 在PsA患者中,骨质疏松症和骨质疏松症的发病率分别为11.7%和33.1%.
- 男性的发病率特别高 (骨质疏松症为9.3%,骨质疏松症为34.3%).
- 下肢体质量指数和椎骨分数与骨质疏松症有关.
结论:
- 牛皮关节炎患者,特别是50岁以下的男性,患骨质疏松症和骨折的风险增加.
- 骨质疏松症患者的下体质指数强调了骨密度查的必要性.
- 早期的骨矿物密度测试和治疗对于治疗PsA骨质疏松症至关重要.
相关概念视频
01:29Bone Disorders
3.5K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.5K
01:31Osteoclasts in Bone Remodeling
2.9K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
2.9K