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在HepG2细胞中长期释放的氧化的抗增殖,迁移和克隆效应

Rakhi Bormon1, Ekta Srivastava2, Rafat Ali1

  • 1Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208016, UP, India. sverma@iitk.ac.in.

Chemical communications (Cambridge, England)
|March 7, 2024
PubMed
概括

新型 purin衍生物释放氧化 (NO) 用于持续的瘤治疗. 这些化合物对肝细胞癌细胞具有显著的抗癌作用,提供了一个有前途的治疗策略.

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相关概念视频

Nitric Oxide Signaling Pathway01:28

Nitric Oxide Signaling Pathway

Nitric oxide (NO), an inorganic gas, acts as a potent second messenger in most animal and plant tissues. NO diffuses out of the cells that produce it and enters the neighboring cells to generate a downstream response. NO synthase (NOS) catalyzes NO production by the deamination of the amino acid arginine. There are three isoforms of NOS. Endothelial cells have endothelial NOS (eNOS), nerve and muscle cells have neuronal NOS (nNOS), and macrophages produce inducible NOS (iNOS) upon exposure to...