与艾滋病毒相关的恶性瘤呈现为急性胰腺炎:一个病例系列
F Madela1, F Anderson1, G B Nhlonzi2
1Department of Surgery, Surgical Gastroenterology, University of KwaZulu-Natal, South Africa.
在患有急性胰腺炎 (AP) 的HIV阳性患者中,瘤是罕见的,但应该怀疑,特别是低CD4计数和胆固醇. 早期成像和内镜评估对于诊断至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
背景情况:
- 急性胰腺炎 (AP) 可能是胰腺或胰腺外瘤的呈现症状.
- 这项研究调查了来自高艾滋病毒流行地区的AP队列中的瘤谱.
研究的目的:
- 描述两组急性胰腺炎队伍中检测到的瘤的病理谱.
- 评估艾滋病毒状态和AP患者的瘤诊断之间的关联.
主要方法:
- 对前性收集的AP患者数据库 (2001-2010年和2013-2015年) 的回顾性评估.
- 使用标准AP诊断标准;检测HIV和CD4计数.
- 对诊断怀疑,严重疾病预测或缺乏临床改善进行的CT扫描.
主要成果:
- 在HIV阴性AP患者中没有发现瘤.
- 七名艾滋病毒阳性AP患者 (4%的HIV+AP队列) 确诊了瘤.
- 瘤包括淋巴瘤 (n=4) 和卡波西肉瘤 (n=3);三名淋巴瘤患者和一名KS患者死亡.
结论:
- 在艾滋病毒阳性患者中,瘤是罕见的 (<4%).
- 怀疑艾滋病毒阳性AP患者的瘤 CD4 计数低和胆固醇.
- 通过截面成像和内镜超声波进行评估.
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