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Updated: Jul 1, 2025

Preparation of Cell-lines for Conditional Knockdown of Gene Expression and Measurement of the Knockdown Effects on E4orf4-Induced Cell Death
13:54

Preparation of Cell-lines for Conditional Knockdown of Gene Expression and Measurement of the Knockdown Effects on E4orf4-Induced Cell Death

Published on: October 21, 2012

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人类腺病毒PI3K-Akt激活剂E4orf1被瘤抑制剂p53准

Lilian Göttig1, Simone Jummer1, Luisa Staehler1

  • 1Institute of Virology, School of Medicine, Technical University of Munich, Munich, Germany.

Journal of virology
|March 7, 2024
PubMed
概括

人类腺病毒使用E4orf1蛋白来激活细胞生存途径. 然而,瘤抑制剂p53通过破坏E4orf1的稳定,防止转化并提供新的抗病毒策略来抑制这种情况.

关键词:
E4orf1 的意思是什么这就是HadVAdV的意思.这就是PI3K-Akt.在 p53 里,p53 是一个 p53 的类型.这是一种瘤抑制剂.

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