降低糖尿病风险 饮食和结肠直肠癌风险
Arianna Natale1, Federica Turati1, Martina Taborelli2
1Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
概括
坚持降低糖尿病风险的饮食 (DRRD) 与降低结直肠癌的风险有关. 这种饮食模式强调全食,限制加工食品,为预防癌症提供了潜在的公共卫生战略.
科学领域:
- 流行病学 流行病学
- 营养科学 营养科学
- 在瘤学瘤学.
背景情况:
- 糖尿病是一种已知的结直肠癌的风险因素.
- 由于发病率和死亡率很高,研究预防癌症的饮食干预措施至关重要.
研究的目的:
- 评估坚持糖尿病降低风险饮食 (DRRD) 与患结直肠癌的风险之间的关联.
主要方法:
- 一项意大利多中心病例控制研究包括1,953例结直肠癌病例和4,154例对照.
- 通过使用经过验证的食物频率问卷来评估饮食摄入量.
- 根据特定食品组的消费和营养素比例计算DRRD得分,并通过后勤回归分析.
主要成果:
- 对DRRD的更高遵守与结直肠癌风险相反相关 (OR=0.77对于最高与最低的三位数).
- DRRD得分增加3个点与风险降低相关 (OR=0.92).
- 这些反向关联在整个人口结构层的结肠和直肠癌中是一致的.
结论:
- 增加对降低糖尿病风险的饮食的坚持显著降低了结直肠癌的风险.
- 实施DRRD建议有可能成为预防结直肠癌的公共卫生战略.
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