左心室辅助装置:昨天,今天和明天
Athanasios Tsiouris1, Mark S Slaughter2, Ashok Kumar Coimbatore Jeyakumar3
1Department of Surgery, Division of Cardiac Surgery, University of Mississippi Medical Center, 2500 N State St, Jackson, MS, 39216, USA. athtsiouris@hotmail.com.
概括
未来的左心室辅助器件 (LVAD) 旨在完全植入并克服目前的感染和电力等局限性. 创新重点是减少电耗和改善能量传输,以获得更好的耐用性和患者结果.
科学领域:
- 生物医学工程 生物医学工程
- 心血管器械 心血管器械
- 医疗技术 医疗技术 医学技术
背景情况:
- 目前的耐用左心室辅助器件 (LVAD) 面临重大挑战,包括成本,电力需求,感染风险,耐用性有限,尺寸限制和血液创伤.
- 这些局限性已经被认识到几十年了,阻碍了广泛采用和最佳的患者护理.
研究的目的:
- 审查LVADs的历史发展.
- 总结开发管道中的新兴LVAD技术,旨在解决当前设备的缺陷.
- 突出未来对完全可植入,持久的LVADs的愿望,这些LVAD可以模仿原生心脏功能,并最大限度地减少并发症.
主要方法:
- 本研究是一篇复习文章.
- 它综合了关于LVADs历史的信息.
- 它总结了当前和未来正在开发中的LVAD设备.
主要成果:
- 未来的LVAD的目标是完全植入,增强耐用性,降低感染风险,脉动性流动,并尽量减少出血和血栓形成.
- 完全植入式系统的关键障碍包括功耗,电池寿命和通过皮肤传输的能量.
- 潜在的解决方案包括减少耗电量,推进电池技术,以及改进通过皮肤传输能源的方法,如自由范围共振电能输送.
结论:
- 为了克服下一代LVADs的技术障碍,需要取得重大进展.
- 在能源输送,电池技术和设备设计方面的持续创新对于开发理想的,完全可植入的LVAD至关重要.
- 审查的管道设备在解决当前LVAD治疗的关键局限性方面表现有前途.
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