工程软弹计量器用于现场生物材料和组织称重
Zixing Zhou1, Tingting Li1, Xiaobin Zhu2
1Department of Engineering Mechanics, School of Civil Engineering, Wuhan University,Wuhan 430072, P.R. China.
ACS biomaterials science & engineering
|March 7, 2024
概括
研究人员开发了软弹计 (SSG) 用于非侵入性水凝称重. 这种方法准确地追踪水凝降解和基因工程组织生长现场,推动生物材料的开发.
科学领域:
- 生物材料科学 生物材料科学
- 生物医学工程 生物医学工程
背景情况:
- 由于其生物相容性和生物降解性,水凝被广泛用于组织工程,再生医学和药物输送.
- 精确和非侵入性地描述水凝降解是至关重要的,但具有挑战性.
研究的目的:
- 开发一种用于in situ水凝称重的新方法.
- 为了能够准确和非侵入性地监测水凝降解过程.
主要方法:
- 使用基于水凝的牺牲模板制造聚二甲基 (PDMS) 软弹测量仪 (SSG).
- 使用SSG长度变化与应用重量之间的线性相关性来确定质量.
- 在缓冲溶液中的水凝在现场进行称重,以追踪降解.
主要成果:
- 开发的SSG能够称重最低湿重约为30毫克的水凝.
- 通过理论,数值和实验分析证实了SSG长度变化和悬挂重量之间的线性关系.
- 成功证明了SSG的可行性和准确性,用于跟踪降解过程中的水凝固体质量变化.
- 展示了SSG在工程组织生长的现场表征方面的潜在应用.
结论:
- 开发的SSG方法为in situ水凝称重提供了一种先进的方法.
- 这种技术为监测水凝降解和工程组织发育提供了高可行性和准确性.
- 在生物医学应用中,SSG方法对推进水凝和生物材料研究具有重大前景.
更多相关视频
09:29Fabrication and Implantation of Miniature Dual-element Strain Gages for Measuring In Vivo Gastrointestinal Contractions in Rodents.
Published on: September 18, 2014
10.3K
07:49Rod-based Fabrication of Customizable Soft Robotic Pneumatic Gripper Devices for Delicate Tissue Manipulation
Published on: August 2, 2016
8.8K
相关概念视频
Measurements of Strain
789
Strain quantifies the deformation of a material under force, typically measured as normal strain, which represents the change in length when compared with the original length. Electrical strain gauges are used for enhanced accuracy. These devices consist of a conductive wire mounted on a paper backing that adheres to the material's surface. These gauges operate on the piezoresistive effect, where the wire's electrical resistance changes in response to mechanical deformation. The strain...
789
Design Example: Strain Gauge Bridge or Wheatstone Bridge
401
The utilization of strain gauges as transducers for converting mechanical strain into electrical signals is a common practice in various engineering applications. These strain gauges are frequently integrated into Wheatstone bridge circuits to accurately measure parameters such as force or pressure. Within this context, each element within the circuit exhibits a resistance that undergoes subtle variations when subjected to mechanical strain. The primary objective is to convert minuscule...
401
