在COVID-19住院患者中的细菌共感染
Ingrid Stéfanie Sarmento Debaco1, Helena Moreira Kluck1, Rômulo Marx1
1Our Lady of Conception Hospital, Conceição Hospital Group, Internal Medicine Service - Porto Alegre (RS), Brazil.
概括
细菌感染发生在22.2%的住院COVID-19患者中,呼吸道感染最常见. 风险因素包括神经疾病和通风,但感染并没有增加死亡率.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 流行病学 流行病学
背景情况:
- 细菌感染是COVID-19住院患者的一个重大问题.
- 了解这些共感染的患病率,风险因素和结果对于患者管理至关重要.
研究的目的:
- 为了确定COVID-19患者中细菌感染的发生率.
- 识别流行细菌病原体,感染源和相关风险因素.
- 分析细菌感染对住院死亡率的影响.
主要方法:
- 一项观察性回顾性研究,涉及672名住院的成年患者,已确认COVID-19.
- 2020年4月至8月期间通过图表审查收集的数据.
- 用于分析感染和死亡风险因素的单变量和多变量强大的波桑回归模型.
主要成果:
- 在22.2%的患者中存在细菌共感染.
- 风险因素包括痴呆症,脑血管疾病,活跃癌症,非侵入性通风,侵入性机械通风和置换疗法.
- 呼吸道感染 (29.36%),血液感染 (25.96%) 和中央静脉导管感染 (25.11%) 是最常见的. 细菌感染与死亡率的增加无关 (p=0.79).
结论:
- 在住院COVID-19患者中观察到高比例的细菌感染,经常来自呼吸道.
- 神经和瘤疾病,以及需要通风和脏替代疗法,被确定为危险因素.
- 在这个队列中,细菌感染和住院死亡率之间没有发现显著的关联.
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