阶段角度作为肌肉质量的预测器在患有炎症性肠道疾病的患者中
Angela Martinha Bongiolo1, Marcos José Machado2, Bruno Ayala Lazarotto3
1Universidade Federal de Santa Catarina, Programa de Pós-Graduação em Ciências Médicas, Florianópolis, SC, Brasil.
Arquivos de gastroenterologia
|March 7, 2024
概括
阶段角度 (PhA) 有效预测炎症性肠病 (IBD) 患者的肌肉质量减少. 这种简单的测量有助于查和监测IBD中营养不良的进展.
科学领域:
- 生物医学科学 生物医学科学
- 临床营养学 临床营养学
- 胃肠病学 胃肠病学
背景情况:
- 在炎症性肠道疾病 (IBD) 中,营养不良和肉类是普遍存在的,导致肌肉代谢.
- 这会影响治疗结果,增加术后并发症,并降低生活质量.
研究的目的:
- 为了确定相角 (PhA) 是否可以预测IBD患者肌肉质量减少.
- 建立PhA作为IBD营养不良的潜在查和监测工具.
主要方法:
- 成年IBD患者的横截面研究.
- 生物电阻分析 (BIA) 用于肌肉质量估计和PhA计算.
- 接收器运行特征 (ROC) 曲线分析,以确定PhA切割点来减少肌肉质量.
主要成果:
- 在PhA和骨肌肉质量 (SMM) 和骨肌肉质量指数 (SMI) 之间发现了显著的相关性.
- 这些关联甚至在患有活跃或严重IBD的患者中仍然存在.
- 确定了特定的PhA截止点:女性≤5.042°,男性≤6.079°,以预测肌肉质量减少.
结论:
- 阶段角 (PhA) 是IBD患者肌肉质量减少的可靠预测指标.
- PhA可以用于查和监测IBD患者的营养不良.
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