在儿童中EOSINOPHILIC ESOPHAGITIS内镜参考分数的准确性
Luciana M Ribeiro1,2, Mário C Vieira1,2, Sabine K Truppel1
1Hospital Pequeno Príncipe, Centro de Gastroenterologia Pediátrica, Curitiba, PR, Brasil.
Arquivos de gastroenterologia
|March 7, 2024
概括
对于EoE (EREFS) 的内镜参考评分有效地识别了儿童的性食道炎. 这一分数显示高特异性和负预测值,有助于早期诊断和预防疾病进展.
科学领域:
- 胃肠病学 胃肠病学
- 儿科内镜术 儿科内镜术
- 过敏和免疫学 过敏和免疫学
背景情况:
- 异性食道炎 (EOE) 是儿童胃肠道健康的一个日益关注的问题.
- 准确的儿童诊断,特别是那些未接受过治疗的儿童,对于有效的管理至关重要.
- 质子抑制剂 (PPI) 治疗可以改变内学发现,需要对以前没有PPI的患者进行评估.
研究的目的:
- 评估对患有食道功能障碍症状的儿童内镜参考评分EoE (EREFS) 的诊断疗效.
- 评估EREFS在一组以前没有接受过PPI治疗的儿科患者中的实用性.
主要方法:
- 一项观察性,横截面研究分析了上部胃肠内镜 (UGE) 报告和图像.
- 对食道活检进行了回顾,以检测异黄素 (≥15种异黄素/HPF).
- 排除了以前接受过PPI治疗或其他导致氨酸友爱症的患者.
主要成果:
- 在2036名患者中,12.2%的内镜检测结果表明了EoE.
- 所有患者中有7.6%的患者患有食道性叶绿素.
- 在EoE患者中,胀 (74%) 和纹 (66.2%) 的发生率明显高于对照组.
- 存在多个内镜检测结果表明高灵敏度 (80.5%) 和特异性 (93.4%).
结论:
- 通过EREFS评估的内镜特征表现出高特异性和负预测价值,用于诊断以前没有使用PPI的儿童的EoE.
- EREFS有助于早期识别EOE特征的炎症和纤维细胞变化.
- 利用EREFS可以通过及时诊断和干预来帮助预防疾病进展.
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