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Updated: Apr 30, 2026

Taste Exam: A Brief and Validated Test
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Published on: August 17, 2018

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C/T-13910 多形态基因定型结果与乳糖耐受性测试结果之间的协议评估:巴西的一项以人口为基础的回顾性研究

Marcia Wehba Esteves Cavichio1, Caio Robledo D'Angioli Costa Quaio2, Wagner Antonio da Rosa Baratela3

  • 1Grupo Fleury, Departamento de Gastroenterologia, São Paulo, SP, Brasil.

Arquivos de gastroenterologia
|March 7, 2024
PubMed
概括

在巴西,C/T-13910多态性测试与乳糖耐受性测试 (LTT) 适度一致,用于诊断乳糖不耐受性. 建议对其他遗传标记物进行进一步的研究,以提高诊断准确度.

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Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
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Description
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The pharmacogenetics of drug transporters is increasingly recognized as a critical factor influencing interindividual variability in drug absorption, distribution, and elimination. These membrane-bound proteins regulate drugs' movement across cellular barriers by actively pumping them out (efflux) or facilitating their uptake (influx). Among the major transporter families, ATP-binding cassette (ABC) and solute carrier (SLC) transporters play particularly prominent roles. Genetic polymorphisms...
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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...
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