关于跨性别男性乳腺癌风险需要考虑的方面:系统审查和风险管理方法
Edvin Wahlström1, Riccardo A Audisio2, Gennaro Selvaggi1
1Department of Plastic Surgery, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.
PloS one
|March 7, 2024
概括
跨性别男性患乳腺癌的风险尚不清楚. 本综述强调了证据不足,并提出了针对这一群体的风险管理方法.
科学领域:
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
- 肯定性别的护理.
背景情况:
- 与 cisgender 女性相比,跨性别男性的乳腺癌风险被了解得很少.
- 跨性别男性可能有不同的乳腺癌风险概况.
- 关于跨性别男性乳腺癌发病率和风险因素的数据有限.
研究的目的:
- 审查影响跨性别男性乳腺癌风险的方面.
- 应用瑞士奶酪模型来分析这些风险.
- 系统地审查已发表的跨性别男性乳腺癌病例.
主要方法:
- 系统的PubMed搜索跨性别男性干预后的乳腺癌病例.
- 纳入标准:跨性别男性,性别失调干预,侵袭性乳腺癌或DCIS.
- 排除标准:性别身份不明,非英语报告. 使用GRADE和瑞士奶酪模型进行风险评估.
主要成果:
- 在文献中发现了28例跨性别男性乳腺癌病例.
- 瑞士奶酪模型揭示了目前针对跨性别男性的乳腺癌预防策略的弱点.
- 对于这个人群中大多数乳腺癌风险方面的证据不足.
结论:
- 突出了管理跨性别男性乳腺癌风险因素的挑战.
- 支持开发一个结构化风险管理方法,用于跨性别男性的乳腺癌.
- 强调需要提高治疗这一群体的临床医生意识.
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