相关实验视频

Updated: Jul 1, 2025

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
10:26

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells

Published on: January 20, 2019

12.2K

在MLL-ENL媒介性白血病的小鼠模型中,Bahcc1对异常表观遗传程序至关重要

Akihide Nakamura1,2, Masahiro Masuya2, Makoto Shinmei1

  • 1Department of Microbiology and Molecular Genetics, Mie University Graduate School of Medicine, Tsu, Japan.

Blood advances
|March 7, 2024
PubMed
概括

一项研究确定了含有1 (Bahcc1) 的Bromo-相邻同质域和卷轴-卷轴作为MLL-ENL介导白血病的关键. 削弱Bahcc1抑制了白血病发生,这表明MLL融合白血病的新治疗点.

更多相关视频

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells10:21

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

Published on: February 21, 2018

10.0K
Comprehensive DNA Methylation Analysis Using a Methyl-CpG-binding Domain Capture-based Method in Chronic Lymphocytic Leukemia Patients13:21

Comprehensive DNA Methylation Analysis Using a Methyl-CpG-binding Domain Capture-based Method in Chronic Lymphocytic Leukemia Patients

Published on: June 16, 2017

10.0K

相关概念视频

Hedgehog Signaling Pathway02:33

Hedgehog Signaling Pathway

The Hedgehog gene (Hh) was first discovered due to its control of the growth of disorganized, hair-like bristles phenotype in Drosophila, much like hedgehog spines. Hh plays a crucial role in the development of organs and the maintenance of homeostasis in both invertebrates and vertebrates. However, while Drosophila has only one Hh protein, mammals have multiple functional Hedgehog proteins - Sonic (Shh), Desert (Dhh), and Indian Hedgehog (Ihh). All of these homologous proteins have adapted to...
7.4K