孕期糖尿病和多民族人口中未来糖尿病的风险
Noa Tsur1, Meir Frankel2, Avivit Cahn3
1Department of Internal Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Journal of diabetes and its complications
|March 7, 2024
概括
与犹太妇女相比,阿拉伯妇女面临更高的妊娠糖尿病 (GDM) 和未来糖尿病的风险. 这凸显了针对阿拉伯妇女,特别是那些有GDM病史的妇女,制定有针对性的糖尿病预防策略的必要性.
科学领域:
- 生殖健康 生殖健康
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 孕期糖尿病 (GDM) 影响母亲和婴儿的健康.
- 在GDM和随后的糖尿病风险的种族差异尚未完全理解.
- 识别高风险人群对于有效的公共卫生干预至关重要.
研究的目的:
- 调查孕妇GDM风险的种族差异.
- 检查种族与未来患糖尿病的风险之间的关联.
- 在不同族群中制定针对糖尿病预防的有针对性的策略.
主要方法:
- 基于人口的回顾性队列研究.
- 对9875名在怀孕期间接受口服葡萄糖耐受性测试 (oGTT) 的妇女的分析 (2007-2017).
- 后勤和考克斯回归分析,以比较阿拉伯和犹太妇女之间的GDM和未来糖尿病风险,以调整混因素.
主要成果:
- 与犹太女性 (10.6%) 相比,阿拉伯女性的GDM发病率明显高 (17.3%).
- 这种增加的GDM风险在调整年龄,BMI和代谢概况 (aOR 1.7) 后仍然存在.
- 阿拉伯族裔独立地与未来糖尿病的风险大幅增加有关 (aHR 5.9),即使考虑到GDM状态.
结论:
- 阿拉伯族裔女性的GDM和随后的糖尿病风险增加.
- 这种未来糖尿病的风险增加是独立于GDM状态的.
- 这些发现强调了加强针对阿拉伯妇女的糖尿病预防工作的必要性,特别是那些有GDM病史的妇女.
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