最近微提取样本技术的进展,用于生物分析
Na Li1, Zhuomin Zhang1, Gongke Li1
1School of Chemistry, Sun Yat-sen University, Guangzhou 510006, China.
Journal of chromatography. A
|March 7, 2024
概括
微提取采样技术通过改善样品制备来增强生物分析. 最近的进展侧重于新的微提取介质和自动化策略,用于检测复杂的生物样本中低度物质.
科学领域:
- 分析化学 分析化学
- 生物化学 生物化学
- 材料科学 材料科学 材料科学
背景情况:
- 生物样本通常含有非常低度的目标物质.
- 复杂的生物矩阵对准确的分析构成重大挑战.
- 有效的样本准备对于成功的生物分析至关重要.
研究的目的:
- 审查微提取样本技术在生物分析的最新进展.
- 讨论微提取介质和采样策略的进展.
- 突出当前的挑战和该领域的未来趋势.
主要方法:
- 关于微提取介质制备的文献综述.
- 微提取采样策略的总结,包括体内,体外和微透析.
- 分析aptamer功能化材料,分子印记聚合物,碳基材料,金属有机框架和共价有机框架的发展.
主要成果:
- 在开发高效的微提取介质方面取得了重大进展.
- 样品制备方法的小型化和自动化是关键的发展.
- 为了满足各种生物分析需求,正在采用各种微提取采样策略.
结论:
- 微提取采样技术对于克服生物分析方面的挑战至关重要.
- 材料和策略的持续创新将推动该领域向前发展.
- 未来的趋势包括进一步的自动化和高度选择性的提取介质的开发.
更多相关视频
09:19Capturing Actively Produced Microbial Volatile Organic Compounds from Human-Associated Samples with Vacuum-Assisted Sorbent Extraction
Published on: June 1, 2022
4.1K
06:18Absorbent Microbiopsy Sampling and RNA Extraction for Minimally Invasive, Simultaneous Blood and Skin Analysis
Published on: February 21, 2019
9.9K
相关概念视频
01:21Sample Preparation for Analysis: Overview
219
Sample preparation is an essential step in the analytical process. It involves preparing a sample so that it can be analyzed accurately. The goal is to extract the analyte, the substance you want to measure, from the sample while removing any components that may interfere with the analysis. Sample preparation techniques vary depending on the physical state of the sample.
Bulk or large solid samples are typically reduced in size using grinding, crushing, or milling techniques to increase the...
Bulk or large solid samples are typically reduced in size using grinding, crushing, or milling techniques to increase the...
219
01:18Sampling Methods: Sample Types
220
Sampling materials are classified into three main types: solid, liquid, and gas.
Solid samples include a variety of substances, such as sediments from water bodies, soil, metals, and biological tissues. Two standard methods for extracting sediments from water bodies are grab sampling and piston coring. Grab sampling involves using a device to collect a discrete sediment sample from the bottom of a water body with minimal disturbance. Grab samples do not always represent the entire area due to...
Solid samples include a variety of substances, such as sediments from water bodies, soil, metals, and biological tissues. Two standard methods for extracting sediments from water bodies are grab sampling and piston coring. Grab sampling involves using a device to collect a discrete sediment sample from the bottom of a water body with minimal disturbance. Grab samples do not always represent the entire area due to...
220