在心房之后的CABG和心律不整复发的风险:AFRODITE研究
Maria Nikolaou1, Gregory Pattakos2, Christos Hitas1
1Cardiology Department, Amalia Fleming General Hospital, Melissia, Attiki, Greece.
概括
在冠状动脉旁路手术 (CABG) 后的术后心房动 (POAF) 并没有影响长期AF复发. 较高的CHA2DS2-VASc得分预测了CABG患者的POAF发展.
科学领域:
- 心脏病学 心脏病学
- 心脏外科手术 心脏外科手术
- 电子生理学 电子生理学
背景情况:
- 手术后心房动 (POAF) 是冠状动脉旁路手术 (CABG) 后的常见并发症,影响20%-40%的患者.
- 需要进一步研究POAF的临床意义和长期影响.
研究的目的:
- 评估隔离CABG的患者心房动 (AF) 在一年内复发的情况.
- 为了比较患有POAF和没有POAF的患者之间的结果.
主要方法:
- 在AFRODITE研究中,有228名50岁以上的患者进行了前性跟踪,这些患者接受了单独的CABG.
- 患者被分为POAF和非POAF组,并在12个月内对AF复发,住院和死亡率进行监测.
- 后勤回归确定了POAF的预测因素,包括CHA2DS2-VASc得分.
主要成果:
- 28.5%的患者在初次住院期间经历了POAF.
- CHA2DS2-VASc评分是POAF发展的最强预测因素 (OR=1.61,p<0.001).
- 虽然POAF患者在医院治疗的结果较差,但长期AF复发率相似 (3.6%对4.8%).
结论:
- 一年后的随访显示,POAF和非POAF组之间的AF复发没有显著差异.
- 较高的CHA2DS2-VASc评分与CABG后发展POAF的可能性增加有关.
- 这些发现表明,尽管短期影响,POAF可能不会显著改变长期AF复发风险.
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