与运动不耐受和轻度创伤性脑损伤后的休息心率相关的症状
Jacinta Thorne1, Sarah C Hellewell, Gill Cowen
1Author Affiliations: School of Allied Health (Ms Thorne and Mr Ring) and Curtin Medical School (Drs Cowen, Jefferson, and Xu), Faculty of Health Sciences, Curtin Health Innovation Research Institute (Mss Thorne and Papini and Drs Hellewell, Cowen, Gozt, Pestell, and Fitzgerald), and School of Population Health (Drs Chih, Thomas, and Xu), Curtin University, Bentley, Western Australia; Perron Institute for Neurological and Translational Science, Nedlands, Western Australia (Mss Thorne and Papini and Drs Hellewell, Gozt, and Fitzgerald); Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia (Mr Ring); School of Psychological Science (Drs Buhagiar and Pestell) and Divisions of Surgery (Dr Thomas) and Emergency Medicine (Dr Celenza), School of Medicine, The University of Western Australia, Nedlands, Western Australia; Neurological Intervention & Imaging Service of Western Australia (Dr Bynevelt) and Emergency Department (Dr Celenza), Sir Charles Gairdner Hospital, Nedlands, Western Australia; The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China (Dr Xu); Sir Charles Gairdner, Royal Perth and Fiona Stanley Hospitals, Perth, Western Australia (Dr Honeybul); Emergency Medicine, Royal Perth Hospital, University of Western Australia (Dr Fatovich); and Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Nedlands, Western Australia (Dr Fatovich).
轻度创伤性脑损伤 (mTBI) 后的症状与客观指标 (如心率和运动耐受性) 有关. 特定的症状概况可能表明自主功能障碍,并预测更长的恢复时间.
科学领域:
- 神经学 神经学
- 运动医学 运动医学
- 康复 康复 康复 康复
背景情况:
- 轻度创伤性脑损伤 (mTBI) 可以引起各种症状,但它们与客观生理标记的联系尚不清楚.
- 了解这些关系对于有效的临床管理和预测康复轨迹至关重要.
研究的目的:
- 调查mTBI后症状,静止心率 (HR) 和运动耐受性之间的关联.
- 探索基于症状的临床形状如何与mTBI恢复有关.
主要方法:
- 一项前性观察性研究包括成人 (18-65岁) 在mTBI后7天内.
- 用脑震荡后症状量表评估症状,测量休息HR,用水牛脑震荡自行车测试评估运动耐受性.
主要成果:
- 更高的症状负担与运动耐受性降低 (P=.002) 和更高的休息HR (P=.048) 有显著的相关性.
- 生理学和前庭眼形状与运动耐受性有关,而与情绪相关的和自主性形状与休息HR的升高有关.
- 一个突出的情绪相关的临床形象预测了mTBI后3个月的持续症状 (aOR=2.08).
结论:
- 基于症状的临床概况,结合休息HR和运动耐受性等客观措施,对于mTBI临床护理至关重要.
- 研究结果表明,在mTBI后,特定症状可能表明自主功能障碍,有助于预后.
相关概念视频
Exercise Stress Test
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...


