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Updated: Jul 1, 2025

De novo Identification of Actively Translated Open Reading Frames with Ribosome Profiling Data
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De novo Identification of Actively Translated Open Reading Frames with Ribosome Profiling Data

Published on: February 18, 2022

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ProTInSeq:通过超深度DNA测序来跟踪转位子插入,以识别翻译的大小ORF

Samuel Miravet-Verde1,2, Rocco Mazzolini3, Carolina Segura-Morales4

  • 1Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr Aiguader 88, 08003, Barcelona, Spain. smiravet@ethz.ch.

Nature communications
|March 7, 2024
PubMed
概括

ProTInSeq识别了以前未被注释的小ORF编码蛋白质 (SEP) 和Mycoplasma pneumoniae中的蛋白质. 这种技术增强了蛋白质组的表征,并揭示了潜在的抗微生物点.

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