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儿童与食物过敏原进行皮肤刺测试的系统反应
Gizem Karkın1, Hacer İlbilge Ertoy Karagöl2, Sinem Polat Terece2
1Department of Pediatrics, Gazi University Faculty of Medicine, Ankara, Turkey.
Turkish archives of pediatrics
|March 7, 2024
概括
对食物过敏原的皮肤刺伤测试 (SPT) 的全身反应 (SRs) 在儿童中很罕见. 然而,SRs的风险,包括过敏反应,在刺痛测试和严重反应的儿童中更高.
科学领域:
- 儿科过敏和免疫学
- 临床皮肤病学临床皮肤病学
- 诊断免疫学 诊断免疫学
背景情况:
- 皮肤刺痛测试 (SPT) 是一种常见的食物过敏诊断工具.
- 虽然通常是安全的,但对儿童的系统反应 (SRs) 存在有限的数据,特别是来自食物过敏原SPT.
- 评估SRs对于完善过敏测试协议至关重要.
研究的目的:
- 专门评估儿童患者在食物过敏原皮肤刺伤试验 (SPT) 期间发生的全身反应 (SRs).
- 在SPT期间识别与SRs相关的风险因素.
主要方法:
- 在2010年至2020年期间,对1852名儿科患者进行了食物过敏原SPT或刺痛测试 (PtoP) 的回顾性分析.
- 在测试期间评估患者记录以确定SRs的发生率.
- 在SPT和PtoP测试之间,以及与患者病史相关的SR率的比较.
主要成果:
- 在标准的SPT中没有观察到局部反应或SRs.
- 在PtoP测试期间,三名患者 (0.16%) 经历了SR,其中包括一个过敏反应病例 (0.05%),主要与豆类和海有关.
- 在接受PtoP测试和患有严重指数反应 (P < .001) 的患者中,SR和过敏反应的发生率显著更高.
结论:
- 儿童中食物过敏原SPT引起的SR和过敏反应的患病率很低.
- 在PtoP测试和在有严重反应史的儿童中,SRs的风险增加.
- 建议保持临床警,特别是在高风险儿科患者进行PtoP测试时.
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