双边非结核菌性中耳炎:一个病例报告
Riko Kajiwara1, Kazuhisa Yamamoto2, Shinya Ohira1
1Department of Otorhinolaryngology, Toho University Omori Medical Center, Tokyo, Japan.
The journal of international advanced otology
|March 7, 2024
概括
非结核性真菌菌菌 (NTM) 感染的治疗具有挑战性. 这项案例研究表明,在与抗生素治疗相结合时,双边Mycobacterium abscessus otitis media可能并不总是需要手术.
科学领域:
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 微生物学 微生物学
背景情况:
- 非结核菌 (NTM) 感染缺乏确定的治疗指南.
- 外科干预与NTM中耳炎抗生素治疗一起发挥的作用也在争论中.
- 双边NTM耳膜炎对保护听力提出了独特的挑战.
研究的目的:
- 报告一种由Mycobacterium abscessus引起的双边中耳炎病例.
- 在双边NTM中耳炎病例中评估抗生素治疗的疗效,包括和没有手术干预.
- 为未来NTM感染的治疗指南提供信息.
主要方法:
- 一个27岁妇女的病例研究,患有双边耳鼻,原因是Mycobacterium.
- 药物敏感性测试指导了抗生素的选择 (克拉里思罗米,阿米卡,伊米).
- 在医疗治疗的同时,在一只耳朵中切除患病组织的手术.
主要成果:
- 耳在治疗后38天内在两只耳朵中消失.
- 受影响的两个耳朵的听力都有所改善.
- 在手术治疗的耳朵和非手术治疗的耳朵之间观察到类似的分辨率和听力改善.
结论:
- 单独使用抗生素治疗可能足以治疗双边NTM中耳炎.
- 在所有NTM中耳炎病例中,手术可能并不必不可少.
- 研究结果表明,可能需要对NTM感染的治疗策略进行修订.
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