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在儿科患者群体中进行放射性不透明标记结肠过境研究 BSPGHAN运动工作组的共识声明
M Papadopoulos1, M Mutalib1, K Nikaki2
1Department of Paediatric Gastroenterology, Evelina London Children's Hospital, St Thomas' Hospital, London, UK.
儿童的功能性便秘 (FC) 是常见的,但用于评估结肠传输时间 (CTT) 的放射性斑标记研究 (ROMS) 缺乏标准化的协议. 本综述旨在为在儿科FC诊断中一致使用ROMS提供指导.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 放射学 放射学是一门学科.
- 临床实践指南 临床实践指南
背景情况:
- 功能性便秘 (FC) 是全球流行的一种儿科疾病.
- 放射性遮标记研究 (ROMS) 是评估FC儿童结肠穿越时间 (CTT) 的标准诊断工具.
- 目前的ROMS协议在方法和应用方面表现出显著的变化.
研究的目的:
- 批判性地评估有关儿科FC的ROMS现有证据.
- 识别ROMS协议中的不一致性及其对诊断准确性的影响.
- 开发基于证据的指导,用于在儿科FC中标准化ROMS的实施.
主要方法:
- 在儿科功能性便秘中对ROMS的文献进行系统审查.
- 分析ROMS协议的变化,包括标记数,研究持续时间和药物使用.
- 在英国儿科胃肠病学,肝病学和营养学会 (BSPGHAN) 运动性工作组 (MWG) 内的专家共识发展.
主要成果:
- 发现ROMS协议中普遍缺乏标准化.
- 标记剂量,研究持续时间,饮食建议和药物管理的突出变化.
- 观察到计算方法的不一致性和肠道准备的必要性.
结论:
- 对ROMS的标准化对于在儿科FC中可靠的CTT评估至关重要.
- 需要基于证据的指导方针来解决协议变异和改善诊断一致性.
- 实施标准化的ROMS将加强对儿童功能性便秘的管理.
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