针作为稳定性COPD患者辅助治疗的有效性:一个多中心,随机化,假控制试验协议
Liuyang Huang1, Sha Yang1, Guixing Xu1
1Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, No. 37, Shi'er Qiao Road, Jinniu District, Chengdu, 610075, Sichuan, China.
BMC complementary medicine and therapies
|March 8, 2024
概括
这项研究研究了针治疗稳定的慢性阻塞性肺病 (COPD),评估其在不同治疗频率的有效性和安全性. 结果将澄清针的治疗方法.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 补充和替代医学 补充和替代医学
- 临床试验 临床试验
背景情况:
- 慢性阻塞性肺病 (COPD) 是全球主要的死亡原因.
- 针作为稳定的COPD的补充疗法具有前景.
- 需要进一步的大规模,长期的研究来验证针的疗效和最佳频率.
研究的目的:
- 评估针治疗稳定性COPD的疗效和安全性.
- 调查针频率和临床结果之间的剂量效应关系.
- 为优化COPD管理中的针方案提供强有力的证据.
主要方法:
- 一个多中心,随机对照试验,涉及550名参与者.
- 分配到每周一次,两次或三次针,假针或等候名单对照组.
- 一个为期12周的治疗阶段,随后是52周的随访期,评估各种临床结果.
主要成果:
- 主要结局:第12周的响应者比例.
- 二次结局:64周的响应率,SGRQ,mMRC,CAT,LFSI,6-MWD,SF-36分数的变化,恶化率和不良事件.
- 分析将比较不同针频率的疗效.
结论:
- 这项研究将提供关于针治疗稳定的COPD的安全性和有效性的强有力的证据.
- 这些发现将指导优化针治疗频率,以改善COPD管理.
- 这项研究旨在澄清COPD中针的剂量反应关系.
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