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胃肠道出血中的内镜血静粉末的现状和临床结果:一项回顾性多中心研究
Zie Hae Lim1, Seung In Seo1, Dae-Seong Myung2
1Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
Clinical endoscopy
|March 8, 2024
概括
静血粉 (UI-EWD) 治疗在胃肠道出血方面表现出高的成功率. 然而,BUN水平升高和活跃出血增加了再出血的风险,需要小心选择患者接受这种治疗.
科学领域:
- 胃肠病学 胃肠病学
- 内镜血液静止症 (Endoscopic Hemostasis) 是一种内镜血液静止症.
- 医疗器械疗法 医疗器械疗法
背景情况:
- 胃肠道 (GI) 流血的管理往往需要有效的静血剂.
- 多中心研究的血静粉在肠道出血的疗效是有限的.
- 研究新的静血粉末对于改善患者的治疗结果至关重要.
研究的目的:
- 评估一种用于消化道出血的新型静血粘合剂粉末 (UI-EWD) 的临床结果.
- 为了确定影响UI-EWD治疗后再出血率的因素.
- 评估UI-EWD在多中心环境中的有效性和安全性.
主要方法:
- 在五家医院对135名因上下肠道出血而接受UI-EWD治疗的患者进行了回顾性研究.
- 数据收集包括患者人口统计,出血病变类型和治疗结果.
- 主要结果:临床和技术成功率. 二次结果:再出血率 (早期,延迟,耐火) 和死亡率.
主要成果:
- UI-EWD实现了高临床和技术成功率 (97%).
- 早期,延迟和耐火性再出血率分别为19.3%,11.1%和12.8%.
- 与早期再出血相关的因素包括血中尿素 (BUN) 水平升高和福雷斯特分类IA/IB (活性出血).
结论:
- UI-EWD是治疗肠道出血的有效血静粉,其成功率很高.
- 患有高BUN和活跃出血 (福雷斯特分类IA/IB) 的患者在治疗后有更高的复出血风险.
- 需要仔细考虑患者因素,以优化UI-EWD治疗结果.
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