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在整个COVID-19疫苗接种时代,在癌症患者的PET/CT上挑战腹淋巴结

Alessia Giordano¹, Rosj Gallicchio¹, Mariarita Milella¹

¹Department of Nuclear Medicine, IRCCS CROB Referral Cancer Center of Basilicata, Rionero in Vulture, Italy.

Current pharmaceutical design

|March 8, 2024

概括

接种COVID-19疫苗可以在癌症患者中引起临时的下淋巴腺病变 (AxL),可能模仿PET/CT扫描中的转移. 仔细审查CT特征和患者病史对于准确诊断和避免不必要的治疗至关重要.

科学领域:

核医学是一种核医学.
在瘤学瘤学.
放射学放射学是一门学科.

背景情况:

接种COVID-19疫苗引发了人们对癌症患者意外检测到下淋巴腺病 (AxL) 的担忧.
良性疫苗接种后反应可能会干扰PET/CT成像 (F-18-FDG,F-18-Choline,Ga-68-DOTATOC),模仿转移.
本研究调查了癌症患者COVID-19疫苗接种后的PET/CT发现及其对疾病管理的影响.

研究的目的:

评估癌症患者在第一剂mRNACOVID-19疫苗接种后的PET/CT发现.
评估这些发现对癌症患者病程管理的影响.

主要方法:

对333名接受PET/CT疫苗接种后癌症患者 (研究组) 进行了评估.
如果SUVmax比率>1.5与逆侧淋巴结相比,则轴心淋巴结 (AxL) 的吸收被认为是显著的.
分析了淋巴结的共同注册的CT (Co-CT) 特征;结节的总成像阳性进行了进一步的调查.

主要成果:

17.1%的接种疫苗的患者在PET扫描上呈阳性淋巴结,明显高于疫情前对照组的2.8% (p < 0.001).
在接种疫苗的组中,84.2%的阳性淋巴结在同CT上表现出良性特征.
只有9名患者需要进一步评估,这表明大多数发现是疫苗接种后良性.

结论:

对PET/CT成像的准确解释至关重要,以防止在接种疫苗的癌症患者中误诊和不必要的干预.
将患者病史与PET/CT后淋巴结的CT分析结合起来,可以帮助区分良性疫苗反应与疾病进展.

关键词:

在 COVID-19 疫情中,聚乙烯/聚乙烯/聚乙烯疫苗疫苗疫苗疫苗癌症癌症癌症癌症癌症淋巴结. 淋巴结. 淋巴结. 淋巴结. 淋巴结. 淋巴结. 淋巴结.淋巴腺病 - 淋巴腺病

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