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Updated: Jul 1, 2025

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
10:44

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达普托米辛通过降低RPS19的表达来抑制多发性骨髓瘤的进展

Yijun Zhuang1, Yin Zhang1, Caiyun Chen1

  • 1Department of Pharmacy, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, 362000, Fujian, China.

Combinatorial chemistry & high throughput screening
|March 8, 2024
PubMed
概括

达普托米辛 (DAP) 对多发性骨髓瘤 (MM) 细胞表现出抗癌作用. DAP抑制了MM细胞的增殖和迁移,同时促进了细胞灭绝,为这种血液性恶性瘤提供了潜在的新疗法.

关键词:
多发性骨髓瘤是一种多发性骨髓瘤.在RPS19中使用.灭症 (apoptosis) 是一种死亡的过程.博尔特佐米布 (Bortezomib) 是一种药物.细胞. 细胞. 细胞.达普米辛是一种菌素.

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