在磁共振成像上异常骨髓信号变化的诊断价值:骨髓活检是必要的吗?
Fatma Arikan1, Yasin Yildiz2, Rabia Ergelen3
1Department of Hematology, Marmara University Hospital, Istanbul, Turkey.
Current medical imaging
|March 8, 2024
概括
在MRI上偶尔发生的骨髓信号变化需要临床和实验室评估,以排除血液恶性瘤. 如果怀疑恶性瘤或发现不确定,建议进行骨髓活检,并对初步变化进行必要的后续检查.
科学领域:
- 放射学 放射学是一门学科.
- 血液学 血液学 血液学
- 在瘤学瘤学.
背景情况:
- 在MRI上确定骨髓信号变化的临床意义至关重要.
- 在没有恶性瘤疑似的患者中,对于偶然发现的骨髓活检的必要性存在不确定性.
研究的目的:
- 评估MRI上偶然检测到的骨髓信号变化的临床意义.
- 在这种情况下,评估骨髓活检的必要性.
主要方法:
- 在MRI上对42名患有偶发骨髓信号变化的患者进行了回顾性分析 (2016年9月 - 2020年1月).
- 在入院或随访期间评估骨髓活检结果,临床数据,实验室结果和恶性瘤诊断.
主要成果:
- 三名患者 (7%) 在入院期间被诊断出患有血液性恶性瘤 (两个多发性骨髓瘤,一个B细胞急性淋巴细胞白血病).
- 一名患者在平均随访时间为40.6个月期间发展出未确定意义的单克隆性胃病变.
结论:
- 偶然的MRI骨髓信号变化需要彻底的临床和实验室评估,以排除血液恶性瘤.
- 当怀疑恶性瘤或发现不明确时,应考虑骨髓活检.
- 定期随访至关重要,因为骨髓信号变化可能是疾病的早期指标.
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