皮皮从出生到青春期前的历史和形态发展
Erim Erdem1, Mustafa Kaplan Caliskan1, Meryem Ilkay Karagul2
1Department of Urology, Mersin University Faculty of Medicine, Mersin, Türkiye.
Investigative and clinical urology
|March 8, 2024
概括
前皮组织从出生到青春期持续成熟,表皮厚度和弹性纤维发生显著变化. 由于前皮的结构变化,前两年是伤口愈合的最佳时间.
科学领域:
- 历史学 历史学 历史学
- 发展生物学 发展生物学
- 儿科解剖学 儿科解剖学
背景情况:
- 前皮从出生到青春期的组织发育没有得到充分的记录.
- 了解皮前皮的成熟对于儿科手术考虑至关重要.
研究的目的:
- 为了研究从出生到青春期前皮肤组织的组织学变化.
- 在皮皮发育过程中识别未被注意到的形态变化.
主要方法:
- 在六个年龄组 (新生儿到8-9岁) 分析了79名健康男孩的前皮样本.
- 组织学检查使用Hematoxylin & Eosin,马森三色素和Verhoeff-Von Gieson染色.
- 对外围神经 (S100) 和血管 (CD105) 的免疫组织化学分析.
主要成果:
- 上皮质厚度在新生儿后显著增加 (p=0.001).
- 弹性纤维的数量和厚度随着年龄的增长而增加.
- 新生儿的周围神经数 (S100) 在新生儿中较低 (p=0.048).
- 原纤维密度和血管数量没有显示出与年龄相关的显著差异.
结论:
- 皮皮经历着持续的青春期前成熟.
- 生命的前两年为前皮中伤口愈合提供了最佳的结构条件.
- 研究结果提供了关于皮皮前皮与年龄相关的组织学变化的见解.
相关概念视频
Development of the Sexual Organs in the Embryo and Fetus
704
Development of the reproductive organs in an embryo starts from a bipotential state. This means the early embryo can develop either male or female reproductive organs. The formation of these organs begins with the growth of gonadal ridges that arise from the intermediate mesoderm during the fifth week of development.
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the...
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the...
704
Penis
4.6K
The penis serves a dual role in sexual reproduction and urination. It consists of three main regions: the glans penis, the body, and the root, each with distinct functions and unique anatomical features.
Anatomy of the Penis
The glans penis, or the head, is the terminal part of the penis and houses the external urethral orifice, the exit point for urine and semen. Covered by the prepuce, or foreskin, the glans is noted for its sensitivity and plays a key role in sexual pleasure. The body of the...
Anatomy of the Penis
The glans penis, or the head, is the terminal part of the penis and houses the external urethral orifice, the exit point for urine and semen. Covered by the prepuce, or foreskin, the glans is noted for its sensitivity and plays a key role in sexual pleasure. The body of the...
4.6K
External Female Genitals
6.3K
The vulva encompasses the external structures of the female reproductive system. At the forefront is the monpubis, a cushion of fatty tissue atop the pubic bone. Once puberty sets in, this area typically grows hair. Extending from just behind the mons pubis are the labia majora (labia = 'lips'; majora = 'larger'), which are larger skin fs olds coated with hair. Nestled within are the labia minora (labia = 'lips'; minora = 'smaller'), which are thinner, more...
6.3K
Changes in the Appendicular Skeleton with Age
2.0K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
2.0K
Development of Blood Vessels
583
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
583
Development of the Heart
936
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
936


