用纹理乳清蛋白缩物稳定的含有黄素的纳米乳液的开发:特征,稳定性和体外消化能力
Morteza Jafari1, Karim Parastouei1, Sepideh Abbaszadeh1
1Health Research Center, Life Style Institute Baqiyatallah University of Medical Sciences Tehran Iran.
Food science & nutrition
|March 8, 2024
概括
挤出改善了原生乳清蛋白缩物质 (NWPC) 的特性,提高了黄素纳米乳液的稳定性和封装效率. 挤出WPC (EWPC) 稳定纳米乳液显示在各种条件下改善了质性质和稳定性.
科学领域:
- 食品科学与技术 食品科学与技术
- 生物材料工程 生物材料工程
- 营养药物输送系统 营养药物输送系统
背景情况:
- 原生乳清蛋白缩物 (NWPC) 在稳定食品乳液方面存在局限性.
- 黄素是一种生物活性化合物,需要有效的输送系统来提高稳定性和生物可用性.
- 挤出加工提供了一种修改蛋白质功能的方法.
研究的目的:
- 调查挤出加工对NWPC性能的影响.
- 开发和表征由挤出WPC (EWPC) 稳定的黄素加载纳米乳液.
- 评估从EWPC稳定纳米乳液中黄素的稳定性和体外释放.
主要方法:
- 在不同的pH值和温度下对NWPC进行挤出.
- 使用EWPC作为稳定剂制备含有黄素的纳米乳液.
- 蛋白质特性 (溶解性,疏水性) 和乳液特性 (活性,稳定性,化指数) 的表征.
- 对EWPC稳定乳液的风湿学分析.
- 在不同条件下 (离子强度,pH,热处理,储存) 评估封装效率和纳米乳液稳定性.
- 在模拟的胃和肠液中进行体外释放研究.
主要成果:
- 挤出加工显著改善了NWPC的溶解性,表面水性和乳液性质.
- 与NWPC (90.8%) 相比,EWPC证明了对黄素纳米乳液的优越稳定能力,导致更高的封装效率 (95.7%).
- 经EWPC稳定的纳米乳液表现出增强的粘度,剪切稀释行为,以及对离子强度,pH值变化,热处理和储存的稳定性.
- 纳米乳液在模拟的肠道条件下显示爆发释放,但在模拟的胃条件下稳定.
结论:
- 挤出是一种有效的方法来增强NWPC的功能性质,用于纳米乳液稳定.
- EWPC 作为黄素纳米乳液的强大的稳定剂,改善封装和稳定性.
- 开发的EWPC稳定纳米乳液系统显示,它有望在食品和营养药物应用中提供黄素,具有受控释放特性.
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