重新审视黄素:对其抗癌潜力的最新审查
Abdur Rauf1, Polrat Wilairatana2, Payal B Joshi3
1Department of Chemistry, University of Swabi, Anbar 23561, Khyber Pakhtunkhwa, Pakistan.
Heliyon
|March 8, 2024
概括
丁醇是一种天然的黄,通过向多个途径,显示出显著的抗癌效应. 本次审查强调了其作为各种癌症的补充疗法以及减轻化疗副作用的潜力.
科学领域:
- 自然产品 化学 化学
- 在瘤学瘤学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 饮食中的多和黄具有预防癌症的特性.
- 在水果和蔬菜中丰富的黄,是关键的化学预防剂.
- 素的抗癌活性源于它与多个分子标和信号通路的相互作用.
研究的目的:
- 审查关于黄素对各种癌症类型的疗效的文献.
- 阐明黄素抗癌作用背后的作用机制.
- 为了突出黄素在癌症治疗中的补充性和协同作用的作用.
主要方法:
- 关于黄素和癌症的研究文献综述.
- 分析分子机制,包括亡,细胞循环停止,血管新生,转移和增殖.
- 检查黄素在克服耐药性和减轻化疗副作用方面的作用.
主要成果:
- 在乳腺癌,结肠直肠癌,肺癌,前列腺癌,肝癌,皮肤癌,胰腺癌,口腔癌和胃癌的临床前模型中,素显示出有效性.
- 机制包括诱导亡,细胞循环停止,减少血管生成,转移和扩散.
- 氨酸具有抗氧化特性,可以防止多克索鲁比诱导的不良影响.
结论:
- 氨酸是一种有前途的天然化合物,用于预防和治疗癌症.
- 它的多方面的机制使其成为补充治疗和克服耐药性的有价值候选人.
- 需要进一步研究黄素的协同作用潜力.
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