心肌梗塞前后认知功能趋势:来自中国健康与退休长度研究的发现
Jing Shang1, Jianye Dong2, Sijia Zhu3
1Department of Psychiatry, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Frontiers in aging neuroscience
|March 8, 2024
概括
心肌梗塞 (MI) 在中国成年人中没有先于或加速认知能力下降. 心脏病发作后的认知功能逐渐下降,与心脏病发作前的趋势相似,与中风模式不同.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 老年学是一门学科.
背景情况:
- 脑卒中与认知功能障碍有关,但心肌梗塞 (MI) 周围的认知变化不太了解,特别是在中国人群中.
- 之前的研究表明,中风前后的认知能力下降,促使人们对MI后的类似模式进行调查.
研究的目的:
- 研究心肌梗塞 (MI) 与认知功能变化之间的关联.
- 评估中国队伍中发生心脏病发作前后的认知趋势.
主要方法:
- 来自中国健康与退休纵向研究的11,287名参与者的队列研究.
- 暴露:自我报告的MI. 结果:五个领域的认知功能得分 (记忆,视觉空间,定向,注意力,全球认知).
- 线性混合模型分析了7年内心脏病患者和对照组的认知趋势.
主要成果:
- 421名参与者经历了心脏病发作. 无论是心脏病发作还是对照组,都显示认知能力逐渐下降.
- 在心脏病发作之前的每年认知能力下降率与对照组相似.
- 发作性心脏病并没有与急性认知能力下降或心脏病后加速下降有关.
结论:
- 与中风不同,心脏病发作与心脏病发作前的认知能力下降没有关联.
- 心肌梗塞 (MI) 在事件发生后的几年中没有导致急性认知衰退或加速衰退.
- 需要进一步的研究,以了解心脏病发作和中风之间的明显认知衰退模式.
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