糖尿病视网膜病变作为亡的潜在危险因素:台湾一项为期13年的全国性基于人口的队列研究
Chun-Ju Lin1,2,3, Alan Y Hsu1,4, Peng-Tai Tien1,5
1Department of Ophthalmology, China Medical University Hospital, China Medical University, Taichung, Taiwan.
Frontiers in epidemiology
|March 8, 2024
概括
糖尿病视网膜病变 (DR) 患者面临着显著更高的发展亡的风险. 成年人的年龄和非吸烟状态进一步增加了这种风险,需要在DR患者中进行主动查以检测ptosis.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 糖尿病视网膜病变 (DR) 是糖尿病患者视力丧失的主要原因.
- 死,或上眼垂落,可以影响视力和生活质量.
- 需要进一步调查DR和死风险之间的关联.
研究的目的:
- 为了确定患有糖尿病视网膜病变 (DR) 的患者发展亡的风险.
- 为了确定与DR患者的ptosis发展相关的风险因素.
主要方法:
- 使用台湾国家健康保险研究数据库 (NHIRD) 进行基于人口的,追溯的,匹配的队列研究.
- 分析包括9,494名DR患者和37,976名匹配的对照从2000年至2012年.
- 统计方法包括T测试,Cox比例危险比率,Wilcoxon排名总和测试,Kaplan-Meier估计器和日志排名测试.
主要成果:
- DR患者表现出显著增加患亡的风险 (aHR [95% CI]:2.76 [1.74-4.38],p < 0.001).
- 成年人的年龄和非吸烟者身份与DR患者中亡的风险更高有关.
- 在DR患者中,不论是高脂血症或高血压并发症,都会观察到死风险的增加.
结论:
- 糖尿病视网膜病变 (DR) 患者患有肺亡的风险较高.
- 女性性别,成年年龄和非吸烟者身份是DR患者肺瘤的危险因素.
- 建议对DR患者进行例行查,并且在进行瘤手术之前应管理潜在的糖尿病.
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