从1990年到2019年,头癌的全球负担
Tianjiao Zhou1,2,3, Weijun Huang1,2,3, Xiaoting Wang1,2,3
1Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
全球头癌 (HNC) 发病率正在上升,但由于更好的治疗方法,死亡率正在下降. 针对性干预对高风险人群至关重要,包括年轻人和老年甲状腺癌患者.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 头癌 (HNC) 是一个重大的全球健康挑战.
- 现有的数据不足以完全了解HNC在全球的影响.
- 改善的预后导致了更好的结果,但疾病的全部范围需要进一步调查.
研究的目的:
- 用2019年全球疾病负担 (GBD) 数据库分析头癌的全球发病率,死亡率和残疾调整寿命年 (DALYs).
- 确定HNC负担的趋势,特别关注性别和年龄组之间的差异.
- 为HNC预防和管理制定有针对性的公共卫生战略提供信息.
主要方法:
- 2019年全球疾病负担 (GBD) 数据库的二次数据分析.
- 对HNC发病率,死亡率和DALYs的流行病学调查.
- 在不同的人口群体中对HNC趋势的比较分析.
主要成果:
- 观察到全球头癌发病率显著增加.
- 尽管发病率上升,但与HNC相关的死亡率和DALYs显著下降.
- 与男性相比,女性的发病率升级率较高.
- 需要特别关注低资源环境中的年轻HNC患者和老年甲状腺癌患者.
结论:
- 改善的预后改善了全球头癌患者的治疗结果.
- 迫切需要战略性资源配置和风险因素控制,以减少HNC死亡率,特别是在弱势群体中.
- 量身定制的干预措施对于解决贫困地区的年轻HNC患者和患有甲状腺癌的老年患者的特殊需求至关重要.
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