维里达斯群链球菌细菌病的临床和微生物学概况;来自南印度的经验
Rajalakshmi Arjun1, Vettakkara Kandy Muhammed Niyas1, Febeena Hussain2
1Department of Infectious Diseases, Kimshealth, Thiruvananthapuram, Kerala, India.
Le infezioni in medicina
|March 8, 2024
概括
病毒群链球菌 (VGS) 引起显著的细菌病,死亡率为19%. 抗微生物耐药性的增加,特别是对青素的耐药性,需要改进物种识别方法,以获得更好的患者结果.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 临床流行病学临床流行病学
背景情况:
- 病毒群链球菌 (VGS) 是导致细菌病和传染性内心炎的重要病原体.
- 关于VGS感染的流行病学和临床特征的数据有限,特别是在印度.
研究的目的:
- 分析VGS细菌病的发病率,临床概况,感染源,并发病症和抗菌素耐药性模式.
- 突出与VGS感染相关的临床意义和死亡率.
主要方法:
- 对从2012年1月到2021年12月的VGS细菌病例电子病历的回顾性分析.
- 使用BacT/ALERT用于血液培养化和VITEK 2用于细菌识别和敏感性测试.
- 数据分析包括发病率,患者人口统计,并发病,感染源和抗菌素敏感性.
主要成果:
- VGS占阳性血液培养的3.2%,患者的中位数年龄为58岁,69%是男性.
- 腹部内感染是最常见的来源 (26%);糖尿病是最常见的并发症 (55%).
- 总体上,青素的敏感性为71%; ceftriaxone的敏感性为92%,在医院死亡率为19%.
结论:
- 病毒性结核病 (VGS) 是导致细菌病的重要原因,相关死亡率高.
- 观察到有关青素和 ceftriaxone 耐药性的比率,因物种而异.
- 建议增加分子识别方法的应用,如MALDI-TOF,以准确识别物种.
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